Results for 'Simon J. A. Buczacki'

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  1.  30
    Mouse models of colorectal cancer as preclinical models.Rebecca E. McIntyre, Simon J. A. Buczacki, Mark J. Arends & David J. Adams - 2015 - Bioessays 37 (8):909-920.
    In this review, we discuss the application of mouse models to the identification and pre‐clinical validation of novel therapeutic targets in colorectal cancer, and to the search for early disease biomarkers. Large‐scale genomic, transcriptomic and epigenomic profiling of colorectal carcinomas has led to the identification of many candidate genes whose direct contribution to tumourigenesis is yet to be defined; we discuss the utility of cross‐species comparative ‘omics‐based approaches to this problem. We highlight recent progress in modelling late‐stage disease using mice, (...)
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  2. Ready-Mades: Ontology and Aesthetics.Simon J. Evnine - 2013 - British Journal of Aesthetics 53 (4):407-423.
    I explore the interrelations between the ontological and aesthetic issues raised by ready-mades such as Duchamp’s Fountain. I outline a hylomorphic metaphysics which has two central features. First, hylomorphically complex objects have matter to which they are not identical. Secondly, when such objects are artefacts (including artworks), it is essential to them that they are the products of creative work on their matter. Against this background, I suggest that ready-mades are of aesthetic interest because they pose a dilemma. Is there (...)
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  3. Believing conjunctions.Simon J. Evnine - 1999 - Synthese 118 (2):201-227.
    I argue that it is rational for a person to believe the conjunction of her beliefs. This involves responding to the Lottery and Preface Paradoxes. In addition, I suggest that in normal circumstances, what it is to believe a conjunction just is to believe its conjuncts.
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  4.  79
    The Historicity of Artifacts: Use and Counter-Use.Simon J. Evnine - 2022 - Metaphysics 5 (1):1-13.
    Inspired by Sara Ahmed’s notion of ‘queer use,’ I present and extend a neo-Aristotelian theory of artifacts to capture what I call ‘counter-use.’ The theory of artifacts is based on the idea that what they are, how they come to be, and what their functions are cannot be understood independently from each other. They come to exist when a maker imposes the concept of their substantial kind onto some matter by working on the matter to make an artifact of that (...)
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  5.  7
    Ramism and the reformation of method: the Franciscan legacy in early modernity.Simon J. G. Burton - 2024 - New York: Oxford University Press.
    The Prologue offers an overview of the Reformation of method from Augustine of Hippo through to the Ramist movement, providing an orientation to the rest of the book. It highlights and explains an important nexus of Realism, exemplarism and illumination fundamental to Ramism. Beginning with Augustine it shows how these themes coalesced into a distinctive Christian philosophy taken up and refined by Franciscans such as Bonaventure of Bagnoregio and John Duns Scotus, as well as by Ramon Lull, the Franciscan-inspired encyclopaedist. (...)
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  6. Constitution and qua objects in the ontology of music.Simon J. Evnine - 2009 - British Journal of Aesthetics 49 (3):203-217.
    Musical Platonists identify musical works with abstract sound structures but this implies that they are not created but only discovered. Jerrold Levinson adapts Platonism to allow for creation by identifying musical works with indicated sound structures. In this paper I explore the similarities between Levinson's view and Kit Fine's theory of qua objects. Fine offers the theory of qua objects as an account of constitution, as it obtains, for example, between a statue and the clay the statue is made out (...)
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  7. Constitution and Composition: Three Approaches to their Relation.Simon J. Evnine - 2011 - ProtoSociology 27:212-235.
    Constitution is the relation between something and what it is made of. Composition is the relation between something and its parts. I examine three different approaches to the relation between constitution and composition. One approach, associated with neo-Aristotelians like Mark Johnston and Kathrin Koslicki, identifies constitution with composition. A second, popular with those sympathetic to classical mereology such as Judith Thomson, defines constitution in terms of parthood. A third, advocated strongly by Lynne Baker, takes constitution to be somehow inconsistent with (...)
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  8. Meme-making: Poaching, Reappropriation, or Bricolage?Simon J. Evnine - manuscript
    Memes are a prominent example of a kind of digital artifact. It is widely agreed that an integral component of meme-making is the way in which it makes use of other existing material. In this paper, I examine three different ways of understanding this making use of. First, it has been seen in economic terms, as a kind of poaching. Secondly, the cultural concept of (re)appropriation has been deployed. Finally, Lévi-Strauss’s notion of bricolage is often mentioned. I argue that despite (...)
     
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  9. Understanding madness?Simon J. Evnine - 1989 - Ratio 2 (1):1-18.
    The paper contrasts two ways of understanding the apparently strange assertions of mad persons, finds them both problematic, and proposes an alternative. The first approach, exemplified by R.D. Laing, is to suppose that the beliefs of the mad person are ordinary but expressed in terms that make them appear irrational. The other approach, advocated by Silvano Arieti, is to take the words at face value but to attribute to the mad person a kind of deviant logic. I suggest, on the (...)
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  10. Essentially Contested Concepts and Semantic Externalism.Simon J. Evnine - 2014 - Journal of the Philosophy of History 8 (1):118-140.
    In 1956, W.B. Gallie introduced his idea of essentially contested concepts. In my paper, I offer a novel interpretation of his theory and argue that his theory, thus interpreted, is correct. The key to my interpretation lies in a condition Gallie places on essentially contested concepts that other interpreters downplay or dismiss: that the use of an essentially contested concept must be derived “from an original exemplar whose authority is acknowledged by all the contestant users of the concept.” This reveals (...)
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  11. The universality of logic: On the connection between rationality and logical ability.Simon J. Evnine - 2001 - Mind 110 (438):335-367.
    I argue for the thesis (UL) that there are certain logical abilities that any rational creature must have. Opposition to UL comes from naturalized epistemologists who hold that it is a purely empirical question which logical abilities a rational creature has. I provide arguments that any creatures meeting certain conditions—plausible necessary conditions on rationality—must have certain specific logical concepts and be able to use them in certain specific ways. For example, I argue that any creature able to grasp theories must (...)
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  12. Learning from one's mistakes: Epistemic modesty and the nature of belief.Simon J. Evnine - 2001 - Pacific Philosophical Quarterly 82 (2):157–177.
    I argue that it is not ideally rational to believe that some of one's current beliefs are false, despite the impressive inductive evidence concerning others and our former selves. One's own current beliefs represent a commitment which would be undermined by taking some of them to be false. The nature of this commitment is examined in the light of Nagel's distinction between subjective and objective points of view. Finally, I suggest how we might acknowledge our fallibility consistently with this special (...)
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  13.  48
    Bodily Dys-Order: Desire, Excess and the Transgression of Corporeal Boundaries.Simon J. Williams - 1998 - Body and Society 4 (2):59-82.
    Taking as its point of departure Leder's phenomenological discussion of the `absent' body, this article explores the nature of human corporeality as a site of transgression. The body, I argue, using a process metaphysic, is first and foremost excessive, driven by human desire rather than animal need: a sensual mode of existence organized around the pleasure/pain axis. To be excessive/transgressive, however, implies the crossing of boundaries or limits which vary according to history and culture, time and place. These issues are (...)
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  14.  81
    Supposition and representation in human reasoning.Simon J. Handley & Jonathan StB. T. Evans - 2000 - Thinking and Reasoning 6 (4):273-311.
    We report the results of three experiments designed to assess the role of suppositions in human reasoning. Theories of reasoning based on formal rules propose that the ability to make suppositions is central to deductive reasoning. Our first experiment compared two types of problem that could be solved by a suppositional strategy. Our results showed no difference in difficulty between problems requiring affirmative or negative suppositions and very low logical solution rates throughout. Further analysis of the error data showed a (...)
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  15. Kinds and conscious experience: Is there anything that it is like to be something?Simon J. Evnine - 2008 - Metaphilosophy 39 (2):185–202.
    In this article I distinguish the notion of there being something it is like to be a certain kind of creature from that of there being something it is like to have a certain kind of experience. Work on consciousness has typically dealt with the latter while employing the language of the former. I propose several ways of analyzing what it is like to be a certain kind of creature and find problems with them all. The upshot is that even (...)
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  16. Epistemic unities.Simon J. Evnine - 2003 - Erkenntnis 59 (3):365 - 388.
    I bring together social ontology and social epistemology by consideringsocial entities (``epistemic unities'') that are constituted by the holdingof epistemic relations between their members. In particular, I focus onthe relation of taking someone as an expert. Among the types of structuresexamined are ones with a single expert and one or more non-experts whomay or may not know of each other's situation; and ones with more thanone expert, including cases in which the relation between the experts ishierarchical and cases in which (...)
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  17.  33
    Natural Freedom and Moral Autonomy: Emile as Parent, Teacher and Citizen.J. Simon - 1995 - History of Political Thought 16 (1):21.
    The following analysis seeks to question Rousseau's assumptions concerning the desirability of an �education from things�. In particular, I will focus on the problematic relationship between, on one hand, the development of Emile's sense of freedom and independence, and on the other, his sense of moral autonomy. It is my contention that moral development necessarily entails both what Rousseau provides, namely a well-developed conception of individuality, and something that is sorely lacking in Rousseau's project. Turning to an analysis of the (...)
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  18. Containing Multitudes: Reflection, Expertise and Persons as Groups.Simon J. Evnine - 2005 - Episteme 2 (1):57-64.
    The thesis of the paper is that persons are similar to a kind of group: multiple-expert epistemic unities (MEUs). MEUs are groups in which there are multiple experts on whom other members of the group model their opinion. An example would be a group of children playing Telephone. Any child nearer the source is an 'expert' for any child further away. I argue that, with certain important qualifications, it is both rational and necessary for persons to treat their future selves (...)
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  19. Personhood and future belief: two arguments for something like Reflection.Simon J. Evnine - 2007 - Erkenntnis 67 (1):91-110.
    This paper offers two new arguments for a version of Reflection, the principle that says, roughly, that if one knew now what one would believe in the future, one ought to believe it now. The most prominent existing argument for the principle is the coherence-based Dutch Strategy argument advanced by Bas van Fraassen (and others). My two arguments are quite different. The first is a truth-based argument. On the basis of two substantive premises, that people’s beliefs generally get better over (...)
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  20.  91
    Can evolutionary psychology learn from the instinct debate?Simon J. Hampton - 2006 - History of the Human Sciences 19 (4):57-74.
    The concept of instinct espoused in psychology in the early 20th century and the contemporary concept of psychological adaptation invite comparison. Definitions of both employ the notions of inheritance, selection, functional specificity, and species typicality. This article examines how psychologists before the rise of behaviourism sought to establish instinct as a psychological phenomenon. One of the consequences of doing so was a decoupling of psychological and physiological forms of instinct. This led to a failure of constraint in the usage of (...)
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  21.  34
    Adaptations for nothing in particular.Simon J. Hampton - 2004 - Journal for the Theory of Social Behaviour 34 (1):35–53.
    An element of the contemporary dispute amongst evolution minded psychologists and social scientists hinges on the conception of mind as being adapted as opposed to adaptive. This dispute is not trivial. The possibility that human minds are both adapted and adaptive courtesy of selection pressures that were social in nature is of particular interest to a putative evolutionary social psychology. I suggest that the notion of an evolved psychological adaptation in social psychology can be retained only if it is accepted (...)
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  22.  41
    Maximalising Providence: Samuel Rutherford's Augustinian Transformation of Scotist Scholasticism.Simon J. G. Burton - 2023 - Journal of Scottish Philosophy 21 (2):151-172.
    In recent years evidence has emerged of the considerable influence of Scotist metaphysics on the Reformed scholasticism of the seventeenth century. One of the figures often named in connection with this Scotist revival is Samuel Rutherford (1600–61), who was one of the most important Scottish theologians of the seventeenth century. Focussing on Rutherford’s maximalist doctrine of providence, this article demonstrates his profound debt to key Scotist philosophical devices. In structuring these concepts, however, it is demonstrated that Rutherford is influenced not (...)
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  23.  14
    Save Us From Being Saved: Girard's Critical Soteriology.Simon J. Taylor - 2005 - Contagion: Journal of Violence, Mimesis, and Culture 12 (1):21-30.
    In lieu of an abstract, here is a brief excerpt of the content:Save Us From Being Saved:Girard's Critical SoteriologySimon J. Taylor (bio)One of the most striking things about the work of René Girard is that it is an overarching critique of what it is to be saved. The paradox that Girard presents us with is that "salvation" is something from which we must be saved. This combination of salvation as something that must be avoided and something we desperately need appears (...)
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  24.  5
    Christocentric Encyclopedism in the Long Fifteenth Century. From Nicholas of Cusa to Bernard de Lavinheta.Simon J. G. Burton - 2024 - Journal of the Warburg and Courtauld Institutes 87:27-58.
    Bernard de Lavinheta is commonly recognised as a seminal figure in Renaissance and early modern encyclopedism. A Spanish Franciscan and close colleague of Jacques Lefèvre d’Étaples, Charles de Bovelles and the Fabrist circle in Paris, he published his Practica compendiosa in 1523, marking a major milestone in the Lullist tradition. Yet the focus on Lavinheta as a pioneer of early modern method has often served to obscure his connection to a long medieval tradition of encyclopedism. Drawing out his links to (...)
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  25. Innate Principles and Radical Interpretation.Simon J. Evnine - 1987 - Locke Studies 18:33.
    This paper suggests that Locke's arguments against innate principles rest on a particular conception of what it is for things to be "in the mind." Understanding that notion in terms of presuppositions for radical interpretation allows us to see how some principle might be considered innate after all.
     
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  26.  19
    Squaring the Shield: William Ridgeway's Two Models of Early Greece.Simon J. Cook - 2014 - History of European Ideas 40 (5):693-713.
    SummaryFrom the early 1880s the Cambridge-trained classicist William Ridgeway had applied cutting-edge anthropological theory to his reading of ancient Greek literature in order to develop an evolutionary account of the continuous development of early Greek social institutions. Then, at the turn of the century, he began to argue that archaeological evidence demonstrated that the Achaean warriors described by Homer were in origin Germanic tribesmen from north of the Alps who had but recently conquered Mycenaean Greece. The present paper inquires as (...)
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  27.  65
    Freud's Ambiguous Concepts.Simon J. Evnine - 1989 - Journal of Speculative Philosophy 3 (2):86 - 99.
    In this paper I propose to say something about why certain key psychoanalytic concepts, particularly that of the unconscious, are special because of a studied, and therapeutically important, ambiguity or paradoxicality which affects them. Before I examine these concepts, however, the first section of this paper discusses some of Sartre's views on psychological explanation. On the one hand, this gives me a way of introducing the dichotomy of self-evident irreducibility and existential lucidity which underlies my account of the unconscious. On (...)
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  28.  19
    The Neuro-Complex: Some Comments and Convergences.Simon J. Williams, Stephen Katz & Paul Martin - 2011 - Mediatropes 3 (1):135-146.
    In this short think-piece we trace the newly emerging and rapidly expanding dimensions and dynamics of the “neuro-complex.” What this amounts to, we suggest, are a series of bio or neuro “convergences” of sorts regarding the brain and mental worlds, which in turn are traceable through what we term the bio-psych, pharma-psych, subjectivity-selves, wellness-enhancement, and the neuroculture-neurofutures relational nexuses. These issues are then illustrated through two brief case studies regarding brain scanning technologies and the problems and prospects of cognitive enhancement. (...)
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  29. Precautionary Paralysis.J. E. H. Simon - manuscript
    A brief examination of the self-negating quality of the precautionary principle within the context of environmental ethics, and its consequent failure, as an ethical guide, to justify large-scale regulation of atmospheric cabon dioxide emissions.
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  30.  44
    Philosophy Through Memes.Simon J. Evnine - 2022 - In Lee C. McIntyre, Nancy Arden McHugh & Ian Olasov, A companion to public philosophy. Hoboken, NJ: Wiley-Blackwell. pp. 311–324.
    A paradigm of a meme, in its contemporary sense, is an image macro – an image copied by users, who customize it by adding their own text according to implicitly prescribed norms. The native medium of philosophy is language, generally in the form of either discursive text or Socratic discussion. This chapter suggests there are two features of human existence that stand to meme‐making in something of the same relation as spontaneous dance does to choreography. These features are bricolage and (...)
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  31.  36
    Illusory intuitions: Challenging the claim of non-exclusivity.Simon J. Handley, Omid Ghasemi & Michal Bialek - 2023 - Behavioral and Brain Sciences 46:e125.
    A person who arrives at correct solutions via false premises is right and wrong simultaneously. Similarly, a person who generates “logical intuitions” through superficial heuristics can likewise be right and wrong at the same time. However, heuristics aren't guaranteed to deliver the logical solution, so the claim that system 1 can routinely produce the alleged system 2 response is unfounded.
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  32.  53
    The Pleasures and Perils of Darwinizing Culture (with Phylogenies).Russell D. Gray, Simon J. Greenhill & Robert M. Ross - 2007 - Biological Theory 2 (4):360-375.
    Current debates about “Darwinizing culture” have typically focused on the validity of memetics. In this article we argue that meme-like inheritance is not a necessary requirement for descent with modification. We suggest that an alternative and more productive way of Darwinizing culture can be found in the application of phylogenetic methods. We review recent work on cultural phylogenetics and outline six fundamental questions that can be answered using the power and precision of quantitative phylogenetic methods. However, cultural evolution, like biological (...)
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  33.  41
    An ethical framework for automated, wearable cameras in health behavior research.Paul Kelly, Simon J. Marshall, Hannah Badland, Jacqueline Kerr, Melody Oliver, Aiden R. Doherty & Charlie Foster - unknown
    Technologic advances mean automated, wearable cameras are now feasible for investigating health behaviors in a public health context. This paper attempts to identify and discuss the ethical implications of such research, in relation to existing guidelines for ethical research in traditional visual methodologies. Research using automated, wearable cameras can be very intrusive, generating unprecedented levels of image data, some of it potentially unflattering or unwanted. Participants and third parties they encounter may feel uncomfortable or that their privacy has been affected (...)
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  34.  40
    Creativity, credit, and copyright in the age of artificial art.Joseph G. Moore & Simon J. Frankel - 2024 - Journal of Aesthetics and Art Criticism 82 (3):265-277.
    ABSTRACT Generative artificial intelligence is transforming the way we make, and think about, art. With prompting from human users, these generative systems now produce aesthetically compelling and seemingly creative works in a variety of artistic domains. In doing so, they challenge the ways we think about artistic credit, about creativity, and about the mechanism of legal copyright, which is meant to protect and promote creativity in a capitalist art market. All of this is currently at play in the courtroom, as (...)
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  35. Formal ontology for biomedical knowledge systems integration.J. M. Fielding, J. Simon & Barry Smith - 2004 - Proceedings of Euromise:12-17.
    The central hypothesis of the collaboration between Language and Computing (L&C) and the Institute for Formal Ontology and Medical Information Science (IFOMIS) is that the methodology and conceptual rigor of a philosophically inspired formal ontology will greatly benefit software application ontologies. To this end LinKBase®, L&C’s ontology, which is designed to integrate and reason across various external databases simultaneously, has been submitted to the conceptual demands of IFOMIS’s Basic Formal Ontology (BFO). With this, we aim to move beyond the level (...)
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  36. Effects of training and instruction on analytic and belief-based reasoning processes.Stephen E. Newstead, Simon J. Handley & Helen L. Neilens - 2009 - Thinking and Reasoning 15 (1):37-68.
    Two studies are reported which demonstrate that analytic responding on everyday reasoning problems can be increased and bias eliminated after training on the law of large numbers. Critical thinking problems involving belief-consistent, neutral, and inconsistent conclusions were presented. Belief bias was eliminated when a written justification of argument strength was elicited. However, belief-based responding was still evident when evaluations of the arguments were elicited using rating scales. This finding demonstrates a dissociation between analytic and belief-based responding as a function of (...)
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  37.  38
    Auditory S-R compatibility: Reaction time as a function of ear-hand correspondence and ear-response-location correspondence.J. Richard Simon, James V. Hinrichs & John L. Craft - 1970 - Journal of Experimental Psychology 86 (1):97.
  38. Population Size and the Rate of Language Evolution: A Test Across Indo-European, Austronesian, and Bantu Languages.Simon J. Greenhill, Xia Hua, Caela F. Welsh, Hilde Schneemann & Lindell Bromham - 2018 - Frontiers in Psychology 9.
  39.  48
    Reactions toward the stimulus source: Analysis of correct responses and errors over a five-day period.J. Richard Simon, John L. Craft & John B. Webster - 1973 - Journal of Experimental Psychology 101 (1):175.
  40. “But Is It Science Fiction?”: Science Fiction and a Theory of Genre.Simon J. Evnine - 2015 - Midwest Studies in Philosophy 39 (1):1-28.
    If science fiction is a genre, then attempts to think about the nature of science fiction will be affected by one’s understanding of what genres are. I shall examine two approaches to genre, one dominant but inadequate, the other better, but only occasionally making itself seen. I shall then discuss several important, interrelated issues, focusing particularly on science fiction : what it is for a work to belong to a genre, the semantics of genre names, the validity of attempts to (...)
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  41.  24
    Reaction time to onset and offset of lights and tones: Reactions toward the changed element in a two-element display.J. Richard Simon, John L. Craft & John B. Webster - 1971 - Journal of Experimental Psychology 89 (1):197.
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  42. «en Aquesta Era Yo Ans Que Vengués En Aquest Loc». : Notes Al Llibre Del Gentil A Propòsit Del Canvi D'opinió Del Savi Jueu Sobre La Resurrecció.J. Ruiz Simon - 2009 - Studia Lulliana 49 (1):71-105.
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  43.  34
    Reaction time in an oddity task: Responding to the "different" element of a three-light display.J. Richard Simon & John L. Craft - 1972 - Journal of Experimental Psychology 92 (3):405.
  44.  22
    Life, death, and monopoly rights in a democratic society.Simon J. Smith - 2002 - American Journal of Bioethics 2 (3):43 – 44.
  45.  22
    Kin Against Kin: Internal Co-selection and the Coherence of Kinship Typologies.Sam Passmore, Wolfgang Barth, Kyla Quinn, Simon J. Greenhill, Nicholas Evans & Fiona M. Jordan - 2021 - Biological Theory 16 (3):176-193.
    Across the world people in different societies structure their family relationships in many different ways. These relationships become encoded in their languages as kinship terminology, a word set that maps variably onto a vast genealogical grid of kinship categories, each of which could in principle vary independently. But the observed diversity of kinship terminology is considerably smaller than the enormous theoretical design space. For the past century anthropologists have captured this variation in typological schemes with only a small number of (...)
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  46.  64
    Better but still biased: Analytic cognitive style and belief bias.Dries Trippas, Gordon Pennycook, Michael F. Verde & Simon J. Handley - 2015 - Thinking and Reasoning 21 (4):431-445.
    Belief bias is the tendency for prior beliefs to influence people's deductive reasoning in two ways: through the application of a simple belief-heuristic and through the application of more effortful reasoning for unbelievable conclusions. Previous research indicates that cognitive ability is the primary determinant of the effect of beliefs on accuracy. In the current study, we show that the mere tendency to engage analytic reasoning is responsible for the effect of cognitive ability on motivated reasoning. The implications of this finding (...)
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  47.  74
    The contributions of convergent thinking, divergent thinking, and schizotypy to solving insight and non-insight problems.Margaret E. Webb, Daniel R. Little, Simon J. Cropper & Kayla Roze - 2017 - Thinking and Reasoning 23 (3):235-258.
    The ability to generate diverse ideas is valuable in solving creative problems ; yet, however advantageous, this ability is insufficient to solve the problem alone and requires the ability to logically deduce an assessment of correctness of each solution. Positive schizotypy may help isolate the aspects of divergent thinking prevalent in insight problem solving. Participants were presented with a measure of schizotypy, divergent and convergent thinking tasks, insight problems, and non-insight problems. We found no evidence for a relationship between schizotypy (...)
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  48. The Anonymity of a Murmur: Internet Memes.Simon J. Evnine - 2018 - British Journal of Aesthetics 58 (3):303-318.
    Memes, of the kind found often on the internet, are an increasingly significant medium of expressive activity. I develop a theory of their ontological nature and, in parallel, an analysis of the concept meme. On my view, memes are abstract artifacts made out of norms for production of instances. The norms say things like ‘use a certain image; add text of a certain kind; the text should be delivered in two chunks, one at the top of the image, one at (...)
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  49.  28
    Can there ever be a non-specific adaptation? Rejoinder.Simon J. Hampton - 2005 - Journal for the Theory of Social Behaviour 35 (3):351–353.
  50.  30
    Informed dissent: a further response.Simon J. Neale - 1987 - Journal of Medical Ethics 13 (1):53-54.
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